Jerome Burne and Bio-Identical Hormone Replacement Therapy: Parts 1 and 2 covered some difficulties with Kent Holtorf’s review article, Are Bioidentical Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than Commonly Used Synthetic Versions in Hormone Replacement Therapy?, relating to a potential conflict of interest (despite a statement to the contrary) and the completeness and quality of the review. For this final examination of Jerome Burne’s Should middle-aged women be taking natural HRT?, we focus on a paper for which we had to guess the identity: Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study. (Again, This Really Is Not Good Enough or TRINGE.) Continue reading
Tag Archives: bioidentical hormones
Jerome Burne is co-author of Food Is Better Medicine Than Drugs (FIBMTD) with
Former Visiting Professor Patrick Holford. FIBMTD has a chapter on Balancing Hormones in the Menopause -The HRT scandal vs natural control: there is a brief discussion of “Natural progesterone – a safer way with hormones”.
Progesterone is given in amounts equivalent to that normally produced by a woman who is ovulating (between 20 and 40 mg a day) and, unlike oestrogen or synthetic progestins, it has no known cancer risk – in fact…quite the opposite. [pg. 167, the reference for this bold assertion is a self-help book, not a journal paper or similar, if you were curious. And, no, no specific page reference or indication that this is a study/trial, in vitro, in vivo or animal.]
Mid-May we noticed that Burne had left a long comment, recommending his own research, on a post about The Alternative that Isn’t: Bioidentical Hormones at Science-Based Pharmacy. Gazing into our crystal ball, we anticipated that a Burne special on the topic must be in progress and so were not surprised to read today’s Should middle-aged women be taking natural HRT? in the Daily Mail. The shorthand version of the remainder of this post is:
No. Not if you are relying upon the Holftorf review to provide a comprehensive overview of the relevant evidence on efficacy and safety.