Tag Archives: IgG test

Anton Emmanuel on why IgG testing for intolerances is not a useful diagnostic tool

Dr Anton Emmanuel is a Senior Lecturer in Gastroenterology at UCL. He has also studied the use of IgG testing kits – specifically, Yorktest testing kits. His research has been referred to (very likely inappropriately) by Yorktest in defence of their products. He is also one of the experts listed as backing Food Intolerance Awareness – which refers people to Yorktest for IgG tests.

When Radio 4’s Case Notes investigated food intolerance, Emmanuel was interviewed re IgG testing. We were surprised to hear him offering a rather (in our opinion, appropriately) negative assessment of the diagnostic value of such tests for identifying food intolerances.

Emmanuel is introduced by the presenter as not being very impressed with testing kits, and describes this process of testing as “not nearly as specific as one would like it to be”. For Emmanuel, the fact that wheat, yeast etc. come up often on these tests probably reflects “as much as anything else, our exposure to these things in our diet” rather than a specific intolerance/allergy.

Emmanuel is not impressed with these tests due to, among other issues:

  • No external standard as to levels which show intolerance: the tests rely on internal standards which aren’t as robust as one might like.
  • The effects in the patients Emmanuel has seen using these tests have largely been unimpressive, period. Even where patients did appear to benefit, results have not been great in the longer term.
  • A slightly leaky gut may lead to an IgG response to various proteins. It is erroneous to tie this response to specific proteins.

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Filed under food intolerance, patrick holford, yorktest

You and Yours on Which? Investigation into Food Intolerance Tests

Listen again while you can: BBC Radio 4’s You and Yours on Which?‘s Investigation into Food Intolerance Testing with participation from Dr Mike Walker of Cambridge Nutritional Sciences Ltd.

One note that should be of particular interest to Patrick Holford, given his claims for IgG testing in the diagnosis of food intolerance, is a significant change in stance by the companies who promote, distribute and carry out such tests. We shall write more about this at a later date but Walker was at pains to stress that the Cambridge Nutritional Sciences’ IgG test is indicative of food intolerance but not diagnostic of food intolerance. The tap-dancing on this point was painful and brought a similar episode to mind involving Patrick Holford and his qualifications. Continue reading

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Filed under allergies, food intolerance, patrick holford, yorktest

Which?, YorkTest and Cambridge Nutritional Sciences Ltd

YorkTest claims that Which? describes IgG as "validated scientific test"
Former Visiting Professor Patrick Holford is still Head of Science and Education at Biocare. It is possible that such impressive titles convince the unwary that Holford has an evidence-base for his supplement, health, lifestyle or self-empowerment-through-testing advice.

Holford frequently recommends IgG testing for the diagnosis of food intolerance although there is currently no clinical validation for such a recommendation and several associations of clinical allergists and immunologists have declared that the tests are without merit.[a],[b] Continue reading

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Filed under allergies, allergy, food intolerance, food sensitivity, Holford, patrick holford, yorktest